Phytochemistry, Pharmacological Activities, Toxicity and Clinical Application of Momordica cochinchinensis

Author(s): Hai-Yue Lan, Bin Zhao, Yu-Li Shen, Xiao-Qin Li, Su-Juan Wang*, Li-Jun Zhang*, Hong Zhang*.

Journal Name: Current Pharmaceutical Design

Volume 25 , Issue 6 , 2019

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Momordica cochinchinensis (Lour.) Spreng (M. cochinchinensis) is a deciduous vine that grows in Southeast Asia. It is known as gac in Vietnam and as Red Melon in English. Gac is reputed to be extremely benificial for health and has been widely used as food and folk medicine in Southeast Asia. In China, the seed of M. cochinchinensis (Chinese name: Mu biezi) is used as traditional Chinese medicine (TCM) for the treatment of various diseases. More than 60 chemical constituents have been isolated from M. cochinchinensis. Modern pharmacological studies and clinical practice demonstrate that some chemical constituents of M. cochinchinensis possess wide pharmacological activities, such as anti-tumor, anti-oxidation, anti-inflammatory, etc. This paper reviews the phytochemistry, pharmacological activities, toxicity, and clinical application of M. cochinchinensis, aiming to bring new insights into further research and application of this ancient herb.

Keywords: Momordica cochinchinensis, phytochemistry, pharmacological activities, toxicity, clinical application, ancient herb.

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Article Details

Year: 2019
Page: [715 - 728]
Pages: 14
DOI: 10.2174/1381612825666190329123436
Price: $58

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