An expeditious three-component synthesis of various biologically important heterocyclic
compounds 5-amino-1,3-diaryl-1H-pyrazole-4-carbonitriles by condensation of aryl aldehydes, malononitrile
and phenylhydrazine derivatives is described. This greener protocol was catalyzed by
L-Proline and proceeded efficiently in solvent at room temperature within 2-15 min.
Keywords: Multicomponent reactions, 1H-pyrazole-4-carbonitriles, L-proline, antimicrobial activity, one-pot of threecomponent,
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