Background: In Iranian Traditional Medicine, Boswellia serrata oleo-gum resins were
used for treatment of "Nisyan". "Nisyan" was equivalent of losing the memory or forgetfulness.
Objective: This review evaluates the traditional claims about the B. serrata on memory and its effectiveness on memory loss.
Methods: We extracted all traditional and modern information about B. serrata oleo-gum preparations on memory from scientific accessible resources (Google Scholar, PubMed, Springer, Science direct, Wiley), non-accessible resources and traditional books.
Results: In traditional texts, "Nisyan" was believed to cause by pouring the waste materials into the brain and is
equal to memory loss in modern medicine. Traditional practitioners cured "Nisyan" by
compounds with inhibiting or cleansing effects against waste materials in the brain or
recommended to use plants with warming effects on the brain. It was believed that B.
serrata had beneficial effects on memory functions by three different mechanisms. The
memory enhancing of B. serrata on memory functions has been shown in recent
pharmacological and clinical trial studies.
Conclusion: Although, there are some documents that encourage us to use B. serrata oleo-gum resins on memory functions, but a gap still exists between these investigations, especially in pregnant and nursing mothers. More investigations with large clinical trials are needed to complete these gaps in order to improve the therapeutic applications of B. serrata on memory functions.