The Immune System Regulation in Sepsis: From Innate to Adaptive

Author(s): Yue Qiu, Guo-wei Tu, Min-jie Ju, Cheng Yang*, Zhe Luo*.

Journal Name: Current Protein & Peptide Science

Volume 20 , Issue 8 , 2019

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Graphical Abstract:


Sepsis, which is a highly heterogeneous syndrome, can result in death as a consequence of a systemic inflammatory response syndrome. The activation and regulation of the immune system play a key role in the initiation, development and prognosis of sepsis. Due to the different periods of sepsis when the objects investigated were incorporated, clinical trials often exhibit negative or even contrary results. Thus, in this review we aim to sort out the current knowledge in how immune cells play a role during sepsis.

Keywords: Sepsis, innate immunity, adaptive immunity, inflammation, protein, immune system.

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Year: 2019
Page: [799 - 816]
Pages: 18
DOI: 10.2174/1389203720666190305164128
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