Microwave-Assisted Efficient One-Pot Synthesis of Nitriles Using Recyclable Magnetite (Fe3O4) Nanoparticles as Catalyst and Water as Solvent: A Greener Approach

(E-pub Ahead of Print)

Author(s): Prashant Chavan*, Suhas Pednekar, Ramesh Chaughule, Anushree Lokur.

Journal Name: Nanoscience & Nanotechnology-Asia

Become EABM
Become Reviewer


Background: There has been an increasing curiosity over the past few years to carry out organic reactions over heterogeneous nanocatalysts. Microwave activation coupled with a nanocatalyst along with water as a reaction medium makes the process further green. Microwave activation as a green process reduces reaction times, enhances product purity and improves chemical yield.

Materials and Methods: Nitrile group chemistry has been explored by many researchers across the globe owing to its interesting properties and its importance in synthetic chemistry. Despite several methods being available for the synthesis of nitriles, microwave assisted synthesis of nitriles using Fe3O4 nanoparticles appears more promising. The present study is intended at developing a recyclable magnetite (Fe3O4) nanoparticles catalyzed protocol towards the synthesis of organonitrile derivatives using one pot reaction.

Results: The above protocol incorporates the use of microwave for heating and water as reaction medium. Several substituted nitriles could be synthesized for excellent yields. The magnetite nanoparticles can be reused for new reaction without significant loss in activity.

Keywords: Fe3O4 Nanoparticles, Microwave, One pot synthesis of Nitrile, Recyclability, Water as Solvent

Rights & PermissionsPrintExport Cite as

Article Details

(E-pub Ahead of Print)
DOI: 10.2174/2210681209666190218144322
Price: $95