Punica granatum L. (pomegranate): A Potential Anti-microbial Agent

(E-pub Ahead of Print)

Author(s): Aida Doostkam, Kamyar Iravani, Shahindokht Bassiri-Jahromi*.

Journal Name: Anti-Infective Agents

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Abstract:

Polyphenols have received a high attention due to their biological functions. Pomegranate (Punica granatum L.) is a rich source of Polyphenols such as tannin, ellagitannin, flavonoids and other phenolic acids.

The potential therapeutic uses of pomegranate appear to be wide diversity. Pomegranate has the strong antioxidant activity, and antimicrobial properties, with potential health interests.

This review draws on a method of systematic narrative review on the anti-microbial potent of different parts of pomegranate has been performed. To obtain related studies, a search in PubMed, Web of Science, Science Direct, Scopus and Google Scholar from 1986 to 2018 was performed. The aim of this review was to present an overview of the aspect and advantages of Punica granatum L and to summarize the present data on the anti-microbial activity of pomegranate compound from in vitro and in vivo tests, animal trial systems and human clinical trials. Also, this review discussed the pomegranate extracts activities and their future potential.

The findings of this review support that the pomegranate might be possibly used in the control and potential therapeutic of some microbial infections. This review highlights the new researchers into the pomegranate efficacy on microbial infections.

Keywords: Phytotherapy; Natural Products; Punica granatum L.; Antimicrobial

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Article Details

(E-pub Ahead of Print)
DOI: 10.2174/2211352517666190215113232