CdSe Quantum Dots Induce Cellular Differentiation in HL-60 Cells

(E-pub Ahead of Print)

Author(s): Amit D. Saran*, Jayesh R. Bellare.

Journal Name: Nanoscience & Nanotechnology-Asia

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CdSe QDs, synthesized using a green micro-emulsion method, have been evaluated for their potential in inducing HL-60 differentiation by employing various biochemical assays and as cellular imaging agents. CdSe QDs have been found to effectively induce differentiation with lower rate of cell apoptosis as compared with the positive control (DMSO). Our results exhibit effective induction of HL-60 differentiation by CdSe QDs implicating their therapeutic role in cancerous cells in addition to their usual application as cell-imaging agents.

Keywords: CdSe, quantum dots, microemulsion, HL60, cell differentiation, cell death, nanomedicine

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Article Details

(E-pub Ahead of Print)
DOI: 10.2174/2210681209666190211160721
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