In the herbal drug pharmaceutical industry, guggul is enjoying emergent consumer acceptance
around the world. In the Indian market, more than fifty formulations of guggul have been
introduced by well-known brands including Himalaya, Patanjali and Baidyanath Pharmaceuticals.
Basically, guggul is the gum resin from Commiphora wightii (syn. Commiphora Mukul). It has been
used to treat various ailments including obesity, osteoarthritis, arthritis, constipation, liver disorders,
inflammation, anemia, diabetes, etc. Including medicinal properties, it is used as a good binding
agent and mixed in various herbal formulations. To review the major phytochemical, medicinal properties
and analytical methods involved in the detection of guggul by using the exhaustive bibliographic
research by means of various scientific engines and databases. Guggul contained approximately
66 phytochemical including gallic acid, quercetin, and guggulsterones E and Z. These phytochemicals
have a wide range of pharmacological activities such as antioxidant, antibacterial, antimutagenic,
antivenom and antitumor. It has been noticed that the mode of action of guggulsterone has
not been fully explored. Pharmacology and toxicological studies are very few. These works have
shown huge literature gap, which is to be fulfilled through the detailed in-vivo and in-vitro studies.