Verbascum sinaiticum: A Rich Source of Antioxidant Phenylethanoid Glycosides

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Author(s): Humaira Yasmeen Gondal*, Roshan Zamir, Muhammad Nisar, Muhammad Iqbal Choudhary.

Journal Name: The Natural Products Journal

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Abstract:

In the current report, antioxidant potential of Verbascum sinaiticum has been studied. Radical scavenging and reducing ability of various solvent extracts and isolated constituents from the aerial parts were evaluated by DPPH, ABTS and FRAP assays. Most active water-soluble part of the ethylacetate fraction afforded six phenylethanoid glycosides (1-6), namely Verbascoside, Eukovoside, Martynoside, Jionoside D, Campenoside I and Campenoside II. Largely, all these constituents exhibited significant antioxidant activity whereas their synergistic effect was found prominent in the parent fraction. This is the first report on the antioxidant activity and the isolation of all these phenylethanoid glycosides from Verbascum sinaiticum.

Keywords: Antioxidant, Verbascum sinaiticum, phenolic glycosides, phenylethanoid glycosides, radical scavenging abilitAntioxidant, radical scavenging ability

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Article Details

(E-pub Ahead of Print)
DOI: 10.2174/2210315509666190129160405
Price: $95