Efficient Synthesis of Novel Thioureidobenzamido Alkyl Naphthols in Molten Tetrabutylammonium Bromide

Author(s): Arman Shokooh Saljooghi , Hojatollah Khabazzadeh* , Moj Khaleghi .

Journal Name: Letters in Organic Chemistry

Volume 16 , Issue 11 , 2019

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Abstract:

A new series of benzamido alkyl naphthols were synthesized from the multi-component reaction of 4-(3′-methylthioureido)benzamide, aromatic aldehydes and 2-naphthol. Molten tetrabutyl ammonium bromide was used as a very efficient medium for this reaction while the use of common organic solvents gave no or poor yields. This method is an interesting instance of using molten salt as a medium in multicomponent reactions.

Keywords: Molten salt, 2-naphthol, thioureidobenzamide, 4-amino benzamide, tetrabutyl ammonium bromide, aronatic aldehydes.

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Article Details

VOLUME: 16
ISSUE: 11
Year: 2019
Page: [906 - 910]
Pages: 5
DOI: 10.2174/1570178616666190123120127
Price: $58

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