Biological Activities of Artemisinin Derivatives Beyond Malaria

Author(s): Xiaoyan Liu, Jianguo Cao, Guozheng Huang*, Qingjie Zhao*, Jingshan Shen.

Journal Name: Current Topics in Medicinal Chemistry

Volume 19 , Issue 3 , 2019

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Abstract:

Artemisinin is isolated from Artemisia annua L. with peroxide-containing sesquiterpene lactone structure. Because of its unique structural characteristics and promising anticancer, antivirus activities, it has recently received increasing attention. The aim of this review is to summarize recent discoveries of artemisinin's novel derivatives with new pharmaceutical effects beyond malaria with a focus on its antitumor and antivirus activity, as well as potential results of combination therapy with other clinical drugs.

Keywords: Anticancer activity, Antiviral activity, Artemisinin, Artemisinin derivatives, Dimer, Trimer.

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Article Details

VOLUME: 19
ISSUE: 3
Year: 2019
Page: [205 - 222]
Pages: 18
DOI: 10.2174/1568026619666190122144217
Price: $58

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