Artemisinin is isolated from Artemisia annua L. with peroxide-containing sesquiterpene lactone
structure. Because of its unique structural characteristics and promising anticancer, antivirus activities,
it has recently received increasing attention. The aim of this review is to summarize recent discoveries
of artemisinin's novel derivatives with new pharmaceutical effects beyond malaria with a focus on
its antitumor and antivirus activity, as well as potential results of combination therapy with other clinical
Keywords: Anticancer activity, Antiviral activity, Artemisinin, Artemisinin derivatives, Dimer, Trimer.
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