Bromotryptophan and its Analogs in Peptides from Marine Animals

Author(s): Elsie C. Jimenez*.

Journal Name: Protein & Peptide Letters

Volume 26 , Issue 4 , 2019

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Graphical Abstract:


Bromotryptophan is a nonstandard amino acid that is rarely incorporated in ribosomally synthesized and post-translationally modified peptides (ribosomal peptides). Bromotryptophan and its analogs sometimes occur in non-ribosomal peptides. This paper presents an overview of ribosomal and non-ribosomal peptides that are known to contain bromotryptophan and its analogs. This work further covers the biological activities and therapeutic potential of some of these peptides.

Keywords: Bromotryptophan and analogs, nonstandard amino acid, proteinogenic and non-proteinogenic amino acids, bromotryptophan- containing peptide, ribosomal and non-ribosomal peptides, conotoxin/conopeptide.

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Article Details

Year: 2019
Page: [251 - 260]
Pages: 10
DOI: 10.2174/0929866526666190119170020
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