The Synthesis and Use of BMS 204352 (MaxiPostTM)

(E-pub Ahead of Print)

Author(s): Renato Dalpozzo* .

Journal Name: Mini-Reviews in Organic Chemistry

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Abstract:

MaxiPostTM is an interesting 3-fluorooxindole derivative, discovered in the late nineties of the last century as potassium channel opener. Since then, two different research fields were discovered: the discovery of new synthetic methods, especially asymmetric ones, and the in vitro and in vivo tests for its use as a drug for different diseases. This mini-review aims to summarize the state of art in both fields.

Keywords: Maxipost, Asymmetric synthesis, drug siscovery, oxindoles

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Article Details

(E-pub Ahead of Print)
DOI: 10.2174/1570193X16666181228100254
Price: $95