Necrotizing enterocolitis (NEC) is a frequent and severe life-threatening disease affecting
the gastrointestinal tract of preterm infants. Given that NEC occurs in a well-defined population
of patients, there might be a considerable benefit in identifying specific pharmacological and nutritional
preventive strategies, that could reduce the incidence of NEC. Amongst nutritional strategies
emphasis has been put on the use of probiotics. Therefore, the aim of this review is to summarize
currently available evidence on the role of probiotics in general, as well as the role of specific probiotic
strains or their combinations, in the prevention of NEC.
Keywords: Premature infant, microbiota, sepsis, neonate, NEC, patients, probiotics.
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