Prospective Plant Based Anticancer Lead Molecules

(E-pub Abstract Ahead of Print)

Author(s): Prabhjot Kaur , Vikas Sharma*.

Journal Name: Current Topics in Medicinal Chemistry


Nature has been a source of wide range of products being utilized for the treatment of various diseases like malaria, cancer, diabetes etc. Among these, cancer is emerging as a leading cause of deaths worldwide and development of cross resistance to already established drugs increases the need of novel anticancer drugs. To discover novel anticancer molecules, it is a necessity to unearth the molecules which can act as anticancer agents. Taking natural products in vision, phytoconstituents like terpenoids, flavones, glycosides and alkaloids might act as major source of lead molecules. Considering the anticancer prospectives of phytoconstituents, different unknown lead molecules are summarized in this review. The present review highlights the representative studies of plant based anticancer agents which are classified as per their phytochemical nature. Furthermore, important key points along with important structure activity relationships points regarding selected lead molecules are also discussed.

Keywords: Abietane, Fucoxanthin, Obovatol, Phytoconstituents.

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(E-pub Abstract Ahead of Print)
DOI: 10.2174/1568026619666181224101132
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