Cardiovascular disease (CVD) is the first leading cause of morbidity and mortality in developing and
developed countries. Circulating exosomes have recently been identified as extracellular transporters, detectable
in biological fluids. Exosomes have established a new era in diagnosing diseases, especially CVD. Determination
of exosome profiles, e.g., miRNAs, for different health states such as myocardial injury still requires further studies.
In this review, we will discuss the role of exosomes as a potential biomarker in CVD, with particular
emphasis on recent advances in the methods to study exosomes, isolation, detection, and characterization.
Keywords: Cardiovascular disease, morbidity, mortality, extracellular vesicle, exosome, biomarker.
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