A series of 3-arylspiro[oxirane-2,3'-thiochroman]-4'-one derivatives were synthesized and
characterized by spectroscopy like 1H NMR, 13C NMR, mass spectrometry and elemental analysis.
They were evaluated for their anti-lung cancer activity on human lung cancer cell line A-549 in
DMSO. Compounds under study were found to be potent anti-lung cancer agents with GI50 values less
than 10 with respect to positive control adriamycin.