Cancer is the main cause of death, so the search for active agents to be used in the therapy of this
disease, is necessary. According to studies conducted, substances derived from natural products have shown to
be promising in this endeavor. To these researches, one can associate with the aid of computational chemistry,
which is increasingly gaining popularity, due to the possibility of developing alternative strategies that could
help in choosing an appropriate set of compounds, avoiding unnecessary expenses with resources that would
generate unwanted substance. Thus, the objective of this study was to carry out an approach to several studies
that apply different methods of virtual screening to select natural products with potential anticancer activity.
This review presents reports of studies conducted with some natural products, such as coumarin, quinone, tannins,
alkaloids, flavonoids and terpenes.