Background: Heterocyclic compounds containing nitrogen have been known to possess a very important
role in the field of medicinal chemistry. Indole and its derivatives displayed a wide range of biological
properties such as anti-inflammatory, analgesic, anti-microbial, anti-convulsant, antidepressant, anti-diabetic,
antihelmintic and anti-allergic activities etc. The diverse biological activities exhibited by compounds containing
indole moiety has provided the impetus to explore its anti-microbial activity in order to save the valuable
life of patients.
Objective: The review focuses on the advances in the synthesis of indole derivatives and antimicrobial
properties exhibited by them.
Conclusion: A great deal of work has been done in order to synthesize indole derivatives and to evaluate antimicrobial
potential, as indicated by the review. The information provided in this article may be helpful for the
researchers for the development of efficient antimicrobial drugs.