Clinical Research on the Aortic Elasticity in Patients with Type 1 Diabetes Mellitus Complicated with Hypertension

Author(s): Zheng Wang , Yulei Wan* .

Journal Name: Current Medical Imaging

Volume 15 , Issue 6 , 2019

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Graphical Abstract:


Abstract:

Objective: To investigate the characteristics of aortic elasticity in type 1 diabetes mellitus (DM1) patients with hypertension using dual-source computed tomography (DSCT).

Methods: Subjects were divided into four groups: 31 with hypertension (EH group), 28 with DM1 (DM1 group), 30 with hypertension and DM1 (DM1 + EH group), and 30 healthy volunteers (control group, CG). ECG-gated DSCT was used to measure the cross-sectional area of the aorta in diastole and systole and calculate the aortic elasticity (D). Analysis of variance and multiple linear regression were used for statistical analysis.

Results: Compared with the CG, aortic elasticity (D) in the DM1 group patients was not significantly decreased. Compared with the EH group, the DM1 + EH group showed no significant change. The aortic elasticity (D) in the EH and DM1 + EH groups was significantly lower than that in the CG and DM1 group.

Conclusion: DM1 slightly affects the aortic elasticity of the descending aorta, whereas hypertension exerts the main effect.

Keywords: X-ray computed tomography, hypertension, type 1 diabetes mellitus, thoracic aorta, elasticity, quantitative analysis.

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Article Details

VOLUME: 15
ISSUE: 6
Year: 2019
Page: [585 - 588]
Pages: 4
DOI: 10.2174/1573405614666181105095932
Price: $58

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