An Overview of Synthesis of Indole Alkaloids and Biological Activities of Secondary Metabolites Isolated from Hyrtios Species

Author(s): M. Novanna, K.R. Ethiraj, S. Kannadasan*.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 19 , Issue 3 , 2019

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Abstract:

Marine sponges are a rich source of more than 50% of marine natural compounds that have been isolated from marine organisms. This review article is focused on the importance of biologically active and pharmaceutically important secondary metabolites extracted from one of the important classes of marine sponge Hyrtios sp. This review also deals with reported synthetic routes of some indole alkaloids extracted from the marine sponge Hyrtios sp. A range of bioactivities displayed by indole-based alkaloids is described.

Keywords: Hyrtios sp., marine sponges, indole alkaloids, Hyrtinadine A, Hyrtiosin B, Asperazine.

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Article Details

VOLUME: 19
ISSUE: 3
Year: 2019
Page: [194 - 205]
Pages: 12
DOI: 10.2174/1389557518666181102110537
Price: $58

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