Association Between Adiposity Indices and Blood Pressure is Stronger in Sarcopenic Obese Women

Author(s): Maurilio Tiradentes Dutra*, Karla Gonçalves Martins, Diego Batista Vieira dos Reis, Alessandro de Oliveira Silva, Márcio Rabelo Mota.

Journal Name: Current Hypertension Reviews

Volume 15 , Issue 2 , 2019

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Abstract:

Background: Anthropometric indices are useful to identify excess weight and poor health outcomes. Previous research showed that some indices are correlated to blood pressure (BP) among adults. Yet, these associations are poorly characterized in women with sarcopenic obesity (SO). SO is characterized as the combination of sarcopenia and obesity and has been examined as an emerging cause of disorders and frailty.

Objective: The study aims to examine the association between anthropometric indices and BP in community-dwelling women with and without SO.

Method: 118 women (46.3 ± 15.6 years; 1.56 ± .07m; 66.9 ± 12.5kg) underwent BP and anthropometric assessments. Body weight, height, as well as waist (WC) and hip circumference were measured. Body mass index (BMI), body adiposity index (BAI), waist-to-hip (WHR) and waist-toheight (WHtR) ratio were calculated. SO was identified based on median values of percent body fat and muscle mass. Partial correlation was used to assess the association between adiposity indices and BP adopting age, presence of hypertension and use of antihypertensive medication as controlling variables. The significance level was set at P ≤ .05.

Results: systolic BP was significantly higher in subjects with SO (126.4 ± 14.1 vs 121.0 ± 11.6mmHg, P = .01). Correlations between anthropometric indices and systolic BP were generally higher in women with SO, reaching statistical significance for WC (r = .39, P < .05) and WHtR (r = .30, P < .05) when age was the controlling variable.

Conclusion: The association of adiposity indices and BP is stronger in subjects with SO when compared to those without SO.

Keywords: Blood pressure, sarcopenia, obesity, hypertension, adiposity indices, sarcopenic obesity.

[1]
Al-Daghri NM, Al-Attas OS, Wani K, et al. Sensitivity of various adiposity indices in identifying cardiometabolic diseases in Arab adults. Cardiovasc Diabetol 2015; 14: 101.
[2]
Bergman RN, Stefanovski D, Buchanan TA, et al. A better index of body adiposity. Obesity 2011; 19: 1083-9.
[3]
Patel SA, Deepa M, Shivashankar R, et al. Comparison of multiple obesity indices for cardiovascular disease risk classification in South Asian adults: The CARRS Study. PLoS One 2017; 12: 1-13.
[4]
Cox BD, Whichelow MJ, Prevost AT. The development of cardiovascular disease in relation to anthropometric indices and hypertension in British adults. Int J Obes 1998; 22: 966-73.
[5]
Gus M, Fuchs SC, Moreira LB, et al. Association between different measurements of obesity and the incidence of hypertension. Am J Hypertens 2004; 17: 50-3.
[6]
Fuchs FD, Gus M, Moreira LB, et al. Anthropometric indices and the incidence of hypertension: A comparative analysis. Obes Res 2005; 13: 1515-7.
[7]
Joffres M, Falaschetti E, Gillespie C, et al. Hypertension prevalence, awareness, treatment and control in national surveys from England, the USA and Canada, and correlation with stroke and ischaemic heart disease mortality: A cross-sectional study. BMJ Open 2013; 3: e003423.
[8]
Lloyd-Sherlock P, Beard J, Minicuci N, Ebrahim S, Chatterji S. Hypertension among older adults in low- and middle-income countries: prevalence, awareness and control. Int J Epidemiol 2014; 43: 116-28.
[9]
James PA, Oparil S, Carter BL, et al. 2014 Evidence-based guideline for the management of high blood pressure in adults. Report from the panel members appoints to the Eighth Joint National Commitee (JNC 8). JAMA 2013; 1097: 1-14.
[10]
Waters DL, Baumgartner RN. Sarcopenia and obesity. Clin Geriatr Med 2011; 27: 401-21.
[11]
Jarosz PA, Bellar A. Sarcopenic obesity: An emerging cause of frailty in older adults. Geriatr Nurs (Minneap) 2009; 30: 64-70.
[12]
Lee S, Kim TN, Kim SH. Sarcopenic obesity is more closely associated with knee osteoarthritis than is nonsarcopenic obesity: A cross-sectional study. Arthritis Rheum 2012; 64: 3947-54.
[13]
Stenholm S, Harris T, Rantenen T, Visser M, Kritchevsky SB, Ferrucci L. Sarcopenic obesity-definition, etiology and consequences. Curr Opin Clin Nutr Metab Care 2008; 11: 693-700.
[14]
Janssen I, Shepard DS, Katzmarzyk PT, Roubenoff R. The healthcare costs of sarcopenia in the United States. J Am Geriatr Soc 2004; 52: 80-5.
[15]
Narici MV, Maffulli N. Sarcopenia: Characteristics, mechanisms and functional significance. Br Med Bull 2010; 95: 139-59.
[16]
Sipila S. Body composition and muscle performance during menopause and hormone replacement therapy. J Endocrinol Invest 2003; 26: 893-901.
[17]
Grossman E. Ambulatory blood pressure monitoring in the diagnosis and management of hypertension. Diabetes Care 2013; 36: 307-11.
[18]
Baumgartner R. Body composition in healthy aging. Ann N Y Acad Sci 2000; 904: 437-48.
[19]
Cesari M, Kritchevsky SB, Baumgartner RN, et al. Sarcopenia, obesity, and inflammation - results from the trial of angiotensin converting enzyme inhibition and novel cardiovascular risk factors study. Am J Clin Nutr 2005; 82: 428-34.
[20]
Dutra MT, Avelar BP, Souza VC, et al. Relationship between sarcopenic obesity-related phenotypes and inflammatory markers in postmenopausal women. Clin Physiol Funct Imaging 2017; 37: 205-10.
[21]
Stamler R. Implications of the INTERSALT study. Hypertension (Dallas, Tex 1979) 1991; 17: 16-20.
[22]
Kotchen TA. Obesity-related hypertension: Epidemiology, pathophysiology, and clinical management. Am J Hypertens 2010; 23: 1170-8.
[23]
Ho SY, Lam TH, Janus ED. Waist to stature ratio is more strongly associated with cardiovascular risk factors than other simple anthropometric indices. Ann Epidemiol 2003; 13: 683-91.
[24]
Johnson AR, Milner JJ, Makowski L. The inflammation highway: metabolism accelerates inflammatory traffic in obesity. Immunol Rev 2012; 249: 218-38.
[25]
Gupta S, Kapoor S. Body adiposity index: Its relevance and validity in assessing body fatness of adults. ISRN Obes 2014; 2014: 1-5.
[26]
Dutra M, Gadelha A, Nóbrega O, Lima R. Body adiposity index, but not visceral adiposity index, correlates with inflammatory markers in sarcopenic obese elderly women. Exp Aging Res 2017; 43: 291-304.
[27]
Hage FG. C-reactive protein and hypertension. J Hum Hypertens 2014; 28: 410-5.
[28]
Oliveira RJ, Bottaro M, Júnior JT, Farinatti PTV, Bezerra LA, Lima RM. Identification of sarcopenic obesity in postmenopausal women: A cutoff proposal. Braz J Med Biol Res 2011; 44: 1171-6.
[29]
Vaz A, Slaets AFF, López LR. Comparison of body fat in Brazilian adult females by bioelectrical impedance analysis. J Phys Conf Ser 2012; 4: 407.
[30]
Barazzoni R, Bischoff S, Boirie Y, et al. Sarcopenic obesity: Time to meet the challenge. Clin Nutr 2018; 11(4): 294-305.


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Article Details

VOLUME: 15
ISSUE: 2
Year: 2019
Page: [161 - 166]
Pages: 6
DOI: 10.2174/1573402114666181031145341

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