Background: There is much epidemiological evidence that fruits, vegetables, medicinal
plants, and their phytochemicals could lower the progression and development of various forms of cancer.
The plants are active reservoirs for novel chemical entities and provide a promising resource for the
management of cancer.
Methods: Several analyses have signified that bioactive flavonoids and phenolic acids might be widely
practiced for the management as well as therapy of numerous carcinomas.
A large number of research works are now focusing on natural polyphenolic compounds and trying to
find out new and more effective treatment strategies for cancer patients.
Results: The probable mechanism comprises anti-oxidant, anti-inflammation, apoptosis and induces
inhibition of cell proliferation along with genomic phenomena elaborated in cancer therapy.
Conclusion: In the last five years, studies investigated the antitumor potential of common polyphenolic
groups (phenolic acids, flavonoids, lignins, resveratrol, stilbene, quercetin etc.) exploring the prospective
mechanism, based on epidemiological data thus reporting therapeutic evidence and various clinical