Background: Cardioselective beta-blockers may affect glucose or lipid profiles.
Objective: We sought to compare the effects of two beta-blockers, metoprolol and bisoprolol, as the
most commonly used drugs in cardiology, on glucose and lipid profiles in patients with cardiovascular
Methods: We conducted a retrospective cross-sectional matched study at Prince Sultan Cardiac Center in
Burydah in August 2017. Patient records were screened, and adult patients with cardiovascular disorders
who were treated with a stable dose of metoprolol or bisoprolol were included. Parameters related to
glucose and lipid metabolism were compared using the Student’s t-test between the two groups.
Results and Conclusion: The metoprolol and bisoprolol arms included 204 and 200 patients,