Recent Application of Polystyrene-supported Triphenylphosphine in Solid-Phase Organic Synthesis

Author(s): Lalthazuala Rokhum*, Ghanashyam Bez*.

Journal Name: Current Organic Chemistry

Volume 23 , Issue 6 , 2019

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Graphical Abstract:


Recent years have witnessed a fast development of solid phase synthetic pathways, a variety of solid-supported reagent and its applications in diverse synthetic strategies and pharmaceutical applicability’s. Polymer-supported triphenylphosphine is getting a lot of applications owing to the speed and simplicity in the process. Furthermore, ease of recyclability and reuse of polymer-supported triphenylphosphine added its advantages. This review covers a wide range of useful organic transformations which are accomplished using cross-linked polystyrene-supported triphenylphosphine with the aim of giving renewed interest in the field of organic and medicinal-combinatorial chemistry.

Keywords: Solid-phase synthesis, metal-free, polymer-supported reagents, polymer-supported triphenylphosphine, heterocycles, organocatalysis, organic transformations.

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Article Details

Year: 2019
Page: [643 - 678]
Pages: 36
DOI: 10.2174/1385272822666181026115752
Price: $58

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PDF: 15