Recent Application of Polystyrene-Supported Triphenylphosphine in Solid-Phase Organic Synthesis

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Author(s): Lalthazuala Rokhum*, Ghanashyam Bez.

Journal Name: Current Organic Chemistry

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Recent years have witnessed a fast development of solid phase synthetic pathways, a variety of solid-supported reagent and its applications in diverse synthetic strategies and pharmaceutical applicability’s. Polymer-supported triphenylphosphine is getting a lot of applications owing to the speed and simplicity in the process. Furthermore, ease of recyclability and reuse of polymer-supported triphenylphosphine added its advantages. This review covers a wide range of useful organic transformations which are accomplished using cross-linked polystyrene-supported triphenylphosphine with the aim of giving renewed interest in the field of organic and medicinal-combinatorial chemistry.

Keywords: Solid-phase synthesis; metal-free; polymer-supported reagents; polymer-supported triphenylphosphine; heterocycles; organocatalysis; organic transformations.

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(E-pub Ahead of Print)
DOI: 10.2174/1385272822666181026115752
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