O-Prenylphenylpropanoids represent a group of rare natural products. During the last
twenty years, such phytochemicals have been revealed to possess a great pharmacological potential.
These compounds have been obtained for the most part from plant species of the Rutaceae, Apiaceae,
and Fabaceae families, as well as from fungi and bacteria. In this review we wish to detail the state of
the art about O-prenylphenylpropanoids having in vitro and in vivo anti-microbial properties from different
points of view. The herein cited natural products are effective in inhibiting the virulence of
human oral pathogens.
Keywords: Acetophenones, Anti-microbial activity, Chalcones, Coumarins, Ferulic acid derivatives, Oxyprenylated secondary
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