Benzimidazole Derivatives as Potential Antimicrobial and Antiulcer Agents: A Mini Review

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Author(s): Ali Mohd Ganie, Ayaz Mahmood Dar, Fairooz Ahmad Khan, Bashir Ahmad Dar*.

Journal Name: Mini-Reviews in Medicinal Chemistry

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Here in we report the number of strategies for the synthesis of differently substituted benzimidazole derivatives. The protocols involved in the syntheses of these derivatives were one-pot or multi-component. The characterization studies of these derivatives were carried by using different spectroscopic techniques (1H NMR, 13C NMR and MS) and elemental analyses. The biological screening studies revealed that these benzimidazole derivatives show potential antibacterial as well as antifungal behavior. These benzimidazole derivatives not only depicted potential antiulcer properties but also showed moderate to good anticancer/cytotoxic behavior against different cancer cell lines.

Keywords: Benzimidazoles, Antimicrobial, Antiulcer, Anticancer

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(E-pub Ahead of Print)
DOI: 10.2174/1381612824666181017102930
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