Strain, dose, duration, validated clinical trial studies and scientific substantiation of health claims are
needed in order to define a successful probiotic. In particular, the potency of probiotic differs from strain to strain.
In this view, we aimed to know whether the single strain or multi-strain construct is more beneficial. We found
that the studies were still under debate and mechanisms remain sometimes unclear. No conclusion can be made
based on the strain experimentation. Safety data and significant statistical results for efficacy via well-controlled
clinical trials are needed.
Keywords: Probiotics, health benefits, single strain, safety recommendation, multiple probiotics, gut microbiota.
Rights & PermissionsPrintExport