Background: The fruit of genus Rosa, known as "rose hip", is frequently used in different traditional
medicines. Rose hips have long been used to treat kidney stones, gastroenteric ailments, hypertension and respiratory
problems such as bronchitis, cough and cold.
Aim: This review is focused on the ethnopharmacological uses of rose hip as well as phytochemical and pharmacological
Results: Ethno-medical uses of rose hip have been recorded in many countries since a long time. Approximately,
129 chemical compounds have been isolated and identified from rose hip. This fruit contains some major active
components such as flavonoids, tannins, anthocyanin, phenolic compounds, fatty oil, organic acids and inorganic
compounds. Scientific studies have suggested a wide range of pharmacological activities for rose hip including
antioxidant, anti-inflammatory, anti-obesity, anti-cancer, hepatoprotective, nephroprotective, cardioprotective,
antiaging, anti H. pylori, neuroprotective and antinociceptive activities. In particular, the rose hip powder and
extract have been reported to exert therapeutic effects on arthritis.
Conclusion: Some of the ethnomedical indications of rose hip, such as nephroprotective and gastroproetctive
actions, have been confirmed by preclinical pharmacological studies. Additional investigations on the pharmacological
effects of rose hip as well as evidence from randomized controlled trials are essential to assess the
therapeutic value of this natural product.