Titanium tetrachloride has been successfully used in the benzylation of aromatic
substrates with a series of benzyl alcohols under mild reaction conditions. With
monosubstituted aromatic substrates, ortho and para-substituted products are obtained in
almost comparable amounts. With sterically hindered benzyl alcohol derivatives almost
exclusively para-substitution occurs.
Keywords: Benzyl alcohol, diarylmethanes, friedel crafts reactions, substituted benzyl alcohols, titanium tetrachloride, aromatic
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