Current Status and Future Developments in Synthetic Peptides

Author(s): Bing Yu, Ankang Zhang, Min Zhang, Wenli Wang, Wenlong Li, Youqing Shen, Hailin Cong*.

Journal Name: Current Organic Chemistry

Volume 22 , Issue 20 , 2018

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Abstract:

Rapid developments in protein engineering, immunology and pharmaceutical research have led to immense demands for synthetic polypeptides. Several polypeptides synthesizing strategies are now available, among which solid-phase synthesis and solution- phase synthesis are especially relevant. This review pretended to compare these two synthesizing strategies with no bias, appreciate their advantages, drawbacks and limitations, and forecast their developmental trends. It also introduced several other special synthetic strategies, and their applications were presented in detail.

Keywords: Peptide, oligopeptide, synthetic peptide, solid phase synthesis, solution phase synthesis, microwave-assisted.

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Article Details

VOLUME: 22
ISSUE: 20
Year: 2018
Page: [1951 - 1958]
Pages: 8
DOI: 10.2174/1385272822666181009151945
Price: $58

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