Halides, as important starting materials, construct complex structures and notable
structural motifs in natural products and manufactured drugs. Transition-metalcatalyzed
halides formation has emerged as a particular approach to generating organohalides,
which is predictable to compete as an alternative to more established synthetic methods.
This review attempts to provide different methods to catalyze the synthesis of organohalides
by using different transition metals, as well as their application in synthetic
Keywords: Catalysis, C-X bond, halides formation, halogenated, organohalides, palladium, transition metals.
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