Background: Myxedema heart disease is an extremely rare disease entity and should be
suspected in patients with unexplained heart failure refractory to conventional treatment.
Myxedema coma with co- existent heart disease is not well known and very few cases have been
Conclusion: Here, we present an interesting case of myxedema coma with severe valvular cardiomyopathy
followed by a concise review of the literature with special emphasis on epidemiology,
pathophysiology, diagnosis and therapeutic modalities.
Keywords: Myxedema heart disease, brief review, heart failure, cardiomyopathy, epidemiology, pathophysiology.
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