Preeclampsia is one of the most serious pregnancy - specific medical conditions of increasing
incidence. It remains a major cause of maternal and fetal morbidity and mortality. Although maternal
mortality is especially high in developing countries, preeclampsia and its complications are one of
the top four causes of maternal deaths even in developed societies. Unfortunately, yet the only effective
and definitive treatment of preeclampsia is delivery of the baby and placenta, and its time depends
on the disease severity and gestational age.
In this review, we report principles of management of preeclampsia in the light of current international
Suggested failure of the placental development and significant role of angiogenic factors and their receptors
in etiology of preeclampsia give the possibility for their future use in diagnosis and risk assessment
of the disease and open new chapter of possible solutions also in the field of treatment of this
serious pregnancy complication.
Introduction of an advanced form of therapy that could safely prolong the duration of pregnancy would
be invaluable in the area of preeclampsia management and lowering perinatal complications, especially
in women with early-onset severe preeclampsia.