Recent Advances in Imaging

Recent Advances in Imaging

Medical Imaging Technologies and Methods for Health Care

Medical Imaging Technologies and Methods for Health Care provides timely, evidence-based information that helps readers understand innovations in medical imaging. These innovations are computer / ...
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Use of Biomechanical Engineering Method in Image Registration of Breast

Pp. 35-44 (10)

Fuk-hay Tang


Background: The image registration using positron emission tomography (PET) and magnetic resonance imaging (MRI) has been studied extensively. The purpose of this project is to propose a patient-specific image registration model that can improve both the accuracy and efficiency of the registration process. Large-scale deformation of the breast makes image registration of the breast a challenging task. Usually, a patient undergoes MRI in the prone position and PET in the supine position. Registration of breast in supine position with breast in prone position is a challenge. Methods: Eight cases with corresponding pairs of PET/computed tomography (CT) and MRI breast images were used in this study for the performance of PET/MRI registration. Registration was based on a biomechanical finite element model that could simulate large-scale deformation of the breast under pressure. Results: In this study, an accurate patient-specific registration model was built with a target registration error (TRE) of 4.77±2.20 mm. Conclusion: Image deformation due to the effect of gravity was successfully modeled by the finite element method.


Finite Element Analysis, Breast Modeling, PET and MR Registration.


School of Dentistry and Health Science, Charles Sturt University, Bathurst, New South Wales, Australia.