Use of Biomechanical Engineering Method in Image Registration of Breast
Pp. 35-44 (10)
Background: The image registration using positron emission tomography (PET) and
magnetic resonance imaging (MRI) has been studied extensively. The purpose of this
project is to propose a patient-specific image registration model that can improve both
the accuracy and efficiency of the registration process. Large-scale deformation of the
breast makes image registration of the breast a challenging task. Usually, a patient
undergoes MRI in the prone position and PET in the supine position. Registration of
breast in supine position with breast in prone position is a challenge.
Methods: Eight cases with corresponding pairs of PET/computed tomography (CT)
and MRI breast images were used in this study for the performance of PET/MRI
registration. Registration was based on a biomechanical finite element model that could
simulate large-scale deformation of the breast under pressure.
Results: In this study, an accurate patient-specific registration model was built with a
target registration error (TRE) of 4.77±2.20 mm.
Conclusion: Image deformation due to the effect of gravity was successfully modeled
by the finite element method.
Finite Element Analysis, Breast Modeling, PET and MR Registration.
School of Dentistry and Health Science, Charles Sturt University, Bathurst, New South Wales, Australia.