A Novel One-pot Protocol for the Cu-Catalyzed Synthesis of Nine 2-Aminobenzimidazole Derivatives from o-Phenylenediamine and Trichloroacetonitrile

Author(s): Manijeh Nematpour*, Elham Abedi, Elahe Abedi.

Journal Name: Letters in Organic Chemistry

Volume 16 , Issue 2 , 2019

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Abstract:

The synthesis of a variety of 2-aminobenzimidazoles via a one pot reaction of ophenylenediamine and trichloroacetonitrile catalyzed by copper (II) acetate in THF at room temperature, with good yields is described. Use of simple and readily available starting materials, good to high yields, free ligand, and no column chromatography are important features of this protocol.

Keywords: Trichloroacetonitrile, copper (II) acetate, 2-aminobenzimidazoles, o-phenylenediamine, THF, ligand.

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Article Details

VOLUME: 16
ISSUE: 2
Year: 2019
Page: [99 - 103]
Pages: 5
DOI: 10.2174/1570178615666180914114010
Price: $58

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