An efficient and ligandless catalytic system was developed for the Suzuki-
Miyaura coupling reactions of potassium aryltrifluoroborates in pure water. Using TEAB
as additives, Pd(OAc)2 was found to be very efficient for the Suzuki-Miyaura coupling of
potassium aryltrifluoroborates with various aryl and heteroaryl bromides in pure water
with Na2CO3 as a base, affording the desired products in moderate to excellent yields.
Keywords: Suzuki-Miyaura coupling reaction, potassium aryltrifluoroborate, aryl bromide, heteroaryl bromide, water, palladium acetate.
Rights & PermissionsPrintExport