A Mini-Review: The Therapeutic Potential of Bone Marrow Mesenchymal Stem Cells and Relevant Signaling Cascades

Author(s): Wen Yang, Bo Ma*.

Journal Name: Current Stem Cell Research & Therapy

Volume 14 , Issue 3 , 2019

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Abstract:

Bone marrow mesenchymal stem cells (BMSCs) characterized multi-directional differentiation, low immunogenicity and high portability, serve as ideal “seed cells” in ophthalmological disease therapy. Therefore, in this mini-review, we examined the recent literature concerning the potential application of BMSCs for the treatment of ophthalmological disease, that includes: the cellular activity of BMSCs transplantation, migration and homing, as well as the immuno-modulatory and antiinflammatory effects of BMSCs and signaling involved. Each aspect is complementary to the others and together these aspects promoted further understanding of the potential use of BMSCs in treating ophthalmological diseases.

Keywords: BMSCs, signaling, ophthalmological, bone marrow, mesenchymal stem cells, embryogenesis.

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Article Details

VOLUME: 14
ISSUE: 3
Year: 2019
Page: [214 - 218]
Pages: 5
DOI: 10.2174/1574888X13666180912141228
Price: $58

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