ZnO@SnO2 Mixed Metal Oxide as an Efficient and Recoverable Nanocatalyst for the Solvent Free Synthesis of Hantzsch 1,4-Dihydropyridines

Author(s): Bharatkumar M. Sapkal, Prakash K. Labhane, Shamrao T. Disale, Dhananjay H. More*.

Journal Name: Letters in Organic Chemistry

Volume 16 , Issue 2 , 2019

Graphical Abstract:


An efficient synthesis of Hantzsch 1,4-dihydropyridines via a one-pot three-component reaction of ethyl acetoacetate, substituted aldehydes and ammonium acetate in the presence of ZnO@SnO2 mixed metal oxide nanoparticles under solvent-free conditions has been reported. Compare to the reported reactions, this method shows attractive aspects such as cleaner reaction profile, shorter reaction times, minimum catalyst loading and high yields. Isolated catalysts were reused for new reactions without considerable loss of their catalytic activity.

Keywords: 1, 4-Dihydropyridines, one-pot multi component reaction, ZnO@SnO2 nanoparticles, solvent free, catalyst, metal oxide.

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Article Details

Year: 2019
Page: [139 - 144]
Pages: 6
DOI: 10.2174/1570178615666180907150307
Price: $58

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