Hypertension is a non-transmissible chronic disease with a high prevalence, morbidity, and mortality.
Different strategies for the treatment of hypertension are employed worldwide, but the control of hypertension
remains a major challenge for global health. Many unsuccessful unconventional therapies have been proposed in
recent years, including herbal medicines and the development of small molecules or antibodies that seek to disrupt
the disease’s pathogenesis. Cell-based therapies may be used as replacement or complementary treatment
strategies. The results of recent preclinical studies of cell-based therapies are promising. However, human clinical
trials are scarce, the data are insipid, and many issues have been raised about the safety and efficacy of cell-based
therapies. The present review summarizes research on cell-based therapy for hypertension. We also briefly summarize
relevant clinical trials and discuss future perspectives and possible clinical applications.
Keywords: Chronic non-communicable disease, hypertension, stem-cell therapy, unconventional treatment, herbal medicines, antibodies.
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