Immunosuppression-lipid Metabolism Interplay and Medicinal Plants in Atherosclerosis: A Review

Author(s): Fahimeh Moradi, Robert D.E Sewell, Zahra Lorigooini, Mahmoud Rafieian-Kopaei*.

Journal Name: Current Pharmaceutical Design

Volume 24 , Issue 24 , 2018


Abstract:

Atherosclerosis is a chronic arterial disease responsible for the majority of vascular-related deaths throughout the world. Immune cells and inflammation in conjunction with hyperlipidemia play a key role in atherosclerosis development. Regarding the low efficacy of the synthetic drugs and also the associated negative side effects which can adversely influence health-related quality of life, looking for natural, affordable and non-toxic substances seem necessary. Plant-derived natural products play a critical role in the prevention and treatment of atherosclerosis. In this review, we aimed to outline the most important medicinal herbs effective for atherosclerosis through the impact on immune system.

Keywords: Atherosclerosis, cardiovascular disease, medicinal plants, immune system, chronic arterial disease, hyperlipidemia.

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Article Details

VOLUME: 24
ISSUE: 24
Year: 2018
Page: [2789 - 2793]
Pages: 5
DOI: 10.2174/1381612824666180829105309
Price: $58

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