Atherosclerosis is a chronic arterial disease responsible for the majority of vascular-related deaths
throughout the world. Immune cells and inflammation in conjunction with hyperlipidemia play a key role in atherosclerosis
development. Regarding the low efficacy of the synthetic drugs and also the associated negative side
effects which can adversely influence health-related quality of life, looking for natural, affordable and non-toxic
substances seem necessary. Plant-derived natural products play a critical role in the prevention and treatment of
atherosclerosis. In this review, we aimed to outline the most important medicinal herbs effective for atherosclerosis
through the impact on immune system.
Keywords: Atherosclerosis, cardiovascular disease, medicinal plants, immune system, chronic arterial disease, hyperlipidemia.
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