Chinese Herbal Formulas and Renal Fibrosis: An Overview

Author(s): Yu-Li Shen, Su-Juan Wang, Khalid Rahman, Li-Jun Zhang*, Hong Zhang*.

Journal Name: Current Pharmaceutical Design

Volume 24 , Issue 24 , 2018


Abstract:

All forms of chronic kidney disease (CKD) eventually lead to renal fibrosis irrespective of its origin. It is generally characterized by an excessive accumulation and deposition of extracellular matrix (ECM) and to date, no ideal treatment has been established. Bian-Zheng-Lun-Zhi (syndrome differentiation and treatment), a classic feature of traditional Chinese Medicine (TCM), is a unique method used to diagnose and treat the pathology of a disease. Zheng (syndrome) is used to demonstrate the nature of a disease completely in an extensive and specific manner. Chinese herbal formulas are determined according to TCM theory and this review highlights these formulas and suggests a possible mechanism for their use in the treatment of renal fibrosis.

Keywords: Chinese herbal formula, Bian-Zheng-Lun-Zhi, renal fibrosis, chronic kidney disease, extracellular matrix (ECM), traditional Chinese Medicine (TCM).

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Article Details

VOLUME: 24
ISSUE: 24
Year: 2018
Page: [2774 - 2781]
Pages: 8
DOI: 10.2174/1381612824666180829103355
Price: $58

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