Surgical operations are impossible without administering proper analgesia. Advancement in
the field of anesthesia has invariably resulted in the accomplishment of all surgical processes without
any inconvenience. Admittedly, the use of noble gas is on the decline. The noble gases may not interact
chemically with any other substance under normal temperature and pressure but they may interact with
proteins and lipids. Different anesthetic molecules may stimulate either proteins or lipids in membrane.
There is a connection between the anesthetic molecules and the hydrophobic region of the membrane.
In the present review, we attempt to highlight the interaction between the anesthetic molecule with
proteins and lipids and their effects. We sketched few noble gases and some other existing molecules
such as halothane and alcohol which interacted with proteins and lipids.
Keywords: Anesthesia, interactions, protein, lipids, effect, membrane.
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