Anesthetic Molecule Interaction of Noble Gases with Proteins and Lipids and their Effect: A Review

Author(s): Shyamal Kumar Kundu*, Chiranjib Chakraborty, Shin Yagihara, Seong Lin Teoh, Srijit Das*.

Journal Name: Current Drug Delivery

Volume 15 , Issue 10 , 2018

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Abstract:

Surgical operations are impossible without administering proper analgesia. Advancement in the field of anesthesia has invariably resulted in the accomplishment of all surgical processes without any inconvenience. Admittedly, the use of noble gas is on the decline. The noble gases may not interact chemically with any other substance under normal temperature and pressure but they may interact with proteins and lipids. Different anesthetic molecules may stimulate either proteins or lipids in membrane. There is a connection between the anesthetic molecules and the hydrophobic region of the membrane. In the present review, we attempt to highlight the interaction between the anesthetic molecule with proteins and lipids and their effects. We sketched few noble gases and some other existing molecules such as halothane and alcohol which interacted with proteins and lipids.

Keywords: Anesthesia, interactions, protein, lipids, effect, membrane.

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Article Details

VOLUME: 15
ISSUE: 10
Year: 2018
Page: [1381 - 1392]
Pages: 12
DOI: 10.2174/1567201815666180820101255
Price: $58

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