Human Suicide Risk and Treatment Study

Author(s): Da-Yong Lu*, Peng-Peng Zhu, Hong-Ying Wu, Nagendra Sastry Yarla, Bin Xu, Ting-Ren Lu.

Journal Name: Central Nervous System Agents in Medicinal Chemistry
(Formerly Current Medicinal Chemistry - Central Nervous System Agents)

Volume 18 , Issue 3 , 2018

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Graphical Abstract:


Introduction: Suicide is still a major event of human mortality worldwide. Yet human suicide prediction, prevention and therapeutic systems at this moment are generally ineffective in the clinic. No diagnostic system is reliable for significantly suicidal prevention and mortality reduction. As a result, human suicide etiopathologic investigation (especially at genetic/molecular levels in the clinical settings) is quite necessary. In order to boost human suicide researches, emerging human suicide diagnostic/treatment study will be transformed from clinical symptom observations into new generations of candidate drug targets and therapeutics. To achieve this goal, associations between suicidal etiopathologic identification, genetic/bioinformatics-based diagnostics and putative drug targets must be exploited than ever before. After all, the interaction and relationships between environmental/ genetic/molecular clues and overall patient’s risk prediction (environmental influences and different therapeutic targets/types) should be found out.

Conclusion: In the future, effective clinical suicide prediction, prevention and therapeutic systems can be established via scientific expeditions and causality discovery.

Keywords: Bioinformatics, clinical pharmacology, drug development, environmental influence, human genome, human suicide, mental disorders, neural pathogenesis.

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Article Details

Year: 2018
Page: [206 - 212]
Pages: 7
DOI: 10.2174/1871524918666180817093015
Price: $58

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