Biomacromolecules structures and their interaction between different systems have been
extensively studied in the last years. Nevertheless, in the medicinal context, it has not been studied
deeply. For this reason, the interest to investigate the behavior of different biomacromolecules such us
proteins, organelles, phospholipids, etc. with soft materials has opened new research lines. Computational
and experimental methodologies have tried to answer different questions that have been difficult
to solve, due to the complexity of the phenomenon, as an example, competition between biomacromolecules
and soft materials for a specific organ. In this review, we would like to demonstrate how soft
materials influence the biomacromolecules structures and how to change their response, biodistribution
and also biocompatibility for future applications.
Keywords: Biomacromolecules, Immune response, Metabolism, Organelles, Phospholipids, Proteins.
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