Abstract
Background: The expressive difficulties in patients with Alzheimer’s dementia have been extensively studied, mainly in oral language. However, the deterioration of their writing processes has received much less attention.
Objective: The present study aims to examine the decline of the performance of patients with Alzheimer’s disease in both oral and written picture-naming tasks.
Method: Sixty-four participants (half with Alzheimer’s disease and half healthy elderly) were compared in the oral and written versions of a picture-naming task. Follow-up lasted two and a half years and patients were evaluated every six months.
Results: Cross-sectional data indicate that the controls performed better than the patients, and both groups showed a different pattern of errors. In terms of longitudinal data, the results show a similar pattern of deterioration in both tasks. In terms of errors, lexical-semantics were the most numerous at the beginning and their number remained constant throughout all evaluations. In the case of non-responses, there was a significant increase in the last session, both in oral and written naming.
Conclusion: These results replicate those found in previous studies and highlight the utility of the naming task to detect minimal changes in the evolution of patients with Alzheimer’s disease.
Keywords: Alzheimer`s disease, picture-naming, anomia, writing disorders, cognitive decline, longitudinal study.
Current Alzheimer Research
Title:Oral and Written Naming in Alzheimer’s Disease: A Longitudinal Study
Volume: 15 Issue: 12
Author(s): Maria Gonzalez-Nosti*, Fernando Cuetos and Carmen Martinez
Affiliation:
- University of Oviedo, Asturias, Spain, Hospital of Cabuenes, Asturias,Spain
Keywords: Alzheimer`s disease, picture-naming, anomia, writing disorders, cognitive decline, longitudinal study.
Abstract: Background: The expressive difficulties in patients with Alzheimer’s dementia have been extensively studied, mainly in oral language. However, the deterioration of their writing processes has received much less attention.
Objective: The present study aims to examine the decline of the performance of patients with Alzheimer’s disease in both oral and written picture-naming tasks.
Method: Sixty-four participants (half with Alzheimer’s disease and half healthy elderly) were compared in the oral and written versions of a picture-naming task. Follow-up lasted two and a half years and patients were evaluated every six months.
Results: Cross-sectional data indicate that the controls performed better than the patients, and both groups showed a different pattern of errors. In terms of longitudinal data, the results show a similar pattern of deterioration in both tasks. In terms of errors, lexical-semantics were the most numerous at the beginning and their number remained constant throughout all evaluations. In the case of non-responses, there was a significant increase in the last session, both in oral and written naming.
Conclusion: These results replicate those found in previous studies and highlight the utility of the naming task to detect minimal changes in the evolution of patients with Alzheimer’s disease.
Export Options
About this article
Cite this article as:
Gonzalez-Nosti Maria *, Cuetos Fernando and Martinez Carmen , Oral and Written Naming in Alzheimer’s Disease: A Longitudinal Study, Current Alzheimer Research 2018; 15 (12) . https://dx.doi.org/10.2174/1567205015666180813145402
DOI https://dx.doi.org/10.2174/1567205015666180813145402 |
Print ISSN 1567-2050 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5828 |
Call for Papers in Thematic Issues
New Advances in the Prevention, Diagnosis, Treatment, and Rehabilitation of Alzheimer's Disease
Aims and Scope: Introduction: Alzheimer's disease (AD) poses a significant global health challenge, with an increasing prevalence that demands concerted efforts to advance our understanding and strategies for prevention, diagnosis, treatment, and rehabilitation. This thematic issue aims to bring together cutting-edge research and innovative approaches from multidisciplinary perspectives to address ...read more
Current updates on the Role of Neuroinflammation in Neurodegenerative Disorders
Neuroinflammation is an invariable hallmark of chronic and acute neurodegenerative disorders and has long been considered a potential drug target for Alzheimer?s disease (AD) and dementia. Significant evidence of inflammatory processes as a feature of AD is provided by the presence of inflammatory markers in plasma, CSF and postmortem brain ...read more
Deep Learning for Advancing Alzheimer's Disease Research
Alzheimer's disease (AD) poses a significant global health challenge, with an increasing number of individuals affected yearly. Deep learning, a subfield of artificial intelligence, has shown immense potential in various domains, including healthcare. This thematic issue of Current Alzheimer Research explores the application of deep learning techniques in advancing our ...read more
Diagnostic and therapeutic biomarkers of dementia
Dementia affects 18 million people worldwide. Dementia is a syndrome of symptoms caused by brain disease, usually chronic or progressive, clinically characterized by multiple impairments of higher cortical functions such as memory, thinking, orientation, and learning. In addition, in the course of dementia, cognitive deficits are observed, which often hinder ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Editorial [Hot Topic:Gamma-Secretase Inhibitors and Modulators as a Therapeutic Approach to Alzheimers disease (Guest Editor: Bruno P. Imbimbo)]
Current Topics in Medicinal Chemistry Evidence for Pleiotropic Effects of Statins in Clinical Trials
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Functional, Global and Cognitive Decline Correlates to Accumulation of Alzheimers Pathology in MCI and AD
Current Alzheimer Research Entrainment of the Human Circadian Clock to the Light-Dark Cycle and its Impact on Patients in the ICU and Nursing Home Settings
Current Pharmaceutical Design The Concept of “Neuroprotection” in Neurological Diseases
Current Neuropharmacology Hereditary Haemorrhagic Teleangiectasia: Diagnostic Imaging of Visceral Involvement
Current Pharmaceutical Design Lead Finding for Acetyl Cholinesterase Inhibitors from Natural Origin: Structure Activity Relationship and Scope
Mini-Reviews in Medicinal Chemistry Mucopolysaccharidosis Type III (Sanfilippo Syndrome): Emerging Treatment Strategies
Current Pharmaceutical Biotechnology Flow and Microwave Assisted Synthesis of Medicinally Relevant Indoles
Current Green Chemistry From Biomarkers to Cytokine-like Hormones: Uncovering New Directives for Cognitive Loss and Alzheimer’s Disease
Current Neurovascular Research β-Sheet Breakers for Alzheimers Disease Therapy
Current Drug Targets When Nutraceuticals Reinforce Drugs Side Effects: A Case Report
Current Drug Safety Soothing the Inflamed Brain: Effect of Non-Steroidal Anti-Inflammatory Drugs on Alzheimers Disease Pathology
CNS & Neurological Disorders - Drug Targets Treating Hypertension in the Elderly: Common Problems and Solutions
Current Hypertension Reviews The Role of Biologically Active Ingredients from Chinese Herbal Medicines in the Regulation of Autophagy in Treating Cardiovascular Diseases and Other Chronic Diseases
Current Pharmaceutical Design Epigenetic Mechanisms in Alzheimer's Disease
Current Medicinal Chemistry Ectonucleotidases and Nucleotide/Nucleoside Transporters as Pharmacological Targets for Neurological Disorders
CNS & Neurological Disorders - Drug Targets The Use of Dexmedetomidine in Anesthesia and Intensive Care: A Review
Current Pharmaceutical Design γ-Secretase Inhibitors and Modulators for the Treatment of Alzheimer's Disease: Disappointments and Hopes
Current Topics in Medicinal Chemistry Editorial [Hot topic: Cognitive Enhancing Drugs: A Blessing for Society? (Joris C. Verster)]
Current Drug Abuse Reviews