Frontiers in Stem Cell and Regenerative Medicine Research

Frontiers in Stem Cell and Regenerative Medicine Research

Volume: 8

Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to ...
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Stem Cells in Endocrinology: Facts and Future

Pp. 150-167 (18)

Hugo Mendieta Zeron, Araceli Hinojosa Juarez and Joel Vargas Hernandez

Abstract

The main characteristic of a stem cell is its multipotency that has to be demonstrated experimentally as follows: I) the differentiation pathway can be characterized by specific surface receptor expression; II) it is possible to generate lineage-specific cells in vitro, and III) in a depleted organ the repopulation process can be reached in vivo. In this regard, the scientific activity to propose and improve techniques of stem cell transplant focused on its clinical application in the endocrinological field is being studied extensively. Unfortunately, not a lot is known about stem cell transplantation to cure diseases and we depend a lot on murine studies. The aim of this chapter is to review some of the most important research lines about stem cells that could have a clinical application in endocrinology.

Keywords:

Adrenal insufficiency, Animal studies, Fertility preservation, Hormonal axis, Hypothyroidism, Induced differentiation, Sheehan syndrome, Stem cell, Stem Cell Transplantation, Type 1 diabetes mellitus.

Affiliation:

Faculty of Medicine, Autonomous University of the State of Mexico (UAEMex), “Mónica Pretelini Sáenz” Maternal-Perinatal Hospital (HMPMPS) and Cipres Grupo Medico S.C. (CGM), Toluca, Mexico.