Background: A highly efficient eco-friendly route for the synthesis of pyrazole derivatives
from readily available chalcones/1, 3-diketones and hydrazines in glycerol using sarcosine as a novel
organopromoter has been developed. To the best of our knowledge this is the first report on the use of
sarcosine as an organocatalyst in organic transformations.
Results and Methods: This method manifests several attributes of green chemistry like atomeconomy,
reusability of catalyst, short reaction time and an eco-friendly medium.
Conclusion: The present protocol can serve as a valuable green alternative to the existing methods for
the synthesis of targeted molecules.