In the postmenopausal women, adnexal masses can have numerous etiologies. They can
range from benign to neoplastic, with origins from a variety of organ systems. The diagnostic work
up includes a thorough history, physical exam, as well as potential imaging and laboratory testing.
There should be a low threshold for consultations with oncologists when there are cancer concerns.
Specifically for gynecologic neoplasms, a referral to a gynecologic oncologist should be strongly
considered. In this paper, there is particular attention to ovarian cancer given the gravity of delayed
Keywords: Adnexal mass, postmenopausal, ovarian cancer, ROMA, HE4, CA125, OVA.
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